Anti-Mouse TREM2 (178) In Vivo Antibody - LALAPG

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SKU
ICH1262LALAPG
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$265.00 - $9,690.00

Anti-Mouse TREM2 (178) In Vivo Antibody - LALAPG

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Mouse
Target
TREM2
Concentration
>1.0 mg/ml
Isotype
Mouse IgG2a
Host
Mouse
Buffer
ICH3002
Uniprot
Q99NH8
Background
TREM2 is an innate immune receptor on myeloid cells, particularly microglia, that regulates phagocytosis, survival, and inflammatory responses and is a focus of neurodegeneration research. The recombinant mouse IgG2a clone 178.0, engineered with LALAPG Fc-silencing mutations to minimise effector function, recognises mouse TREM2 and is validated for blocking, ELISA, functional assays, flow cytometry, and in vivo work. This 178.0 LALAPG antibody is supplied low in endotoxin for in vivo use and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. It is a non-therapeutic, research-use-only reagent offering reproducible results for microglial and TREM2-pathway studies.
Other Names
Triggering receptor expressed on myeloid cells 2
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
Blocking, ELISA, Functional Assays, Flow Cytometry, in vivo
Application Notes
This antibody is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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