Anti-Human PD-1 (IB12) Antibody

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SKU
ICH4029A-0.1mg
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$102.00
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
PD-1
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG4 kappa
Host
Humanized
Size
0.1mg
Uniprot
Q15116
Shipping Conditions
Blue ice
Background
PD-1 is an inhibitory immune checkpoint receptor on activated T cells that, when engaged, restrains anti-tumour immunity, making it a central target in immuno-oncology research. Clone IB12 is a human IgG4-kappa monoclonal antibody against human PD-1, suited to checkpoint-blockade and T-cell activation studies. Anti-PD-1 clone IB12 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. With consistent lot-to-lot performance, IB12 is a reliable reagent for tumour immunology and preclinical checkpoint research. It is a non-therapeutic product intended strictly for research use only.
Other Names
Programmed cell death protein 1, Pdcd1, CD279
Clone
IB12
Specificity
Detects human PD-1.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
This antibody is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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