Anti-Human HLA-DR (L243) Antibody: Fc Biotinylated

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SKU
ICH1026B
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$200.00 - $1,700.00

Anti-Human HLA-DR (L243) Antibody: Fc Biotinylated

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
HLA-DR
Concentration
1.0 mg/ml
Isotype
Mouse IgG2a
Host
Mouse
Aggregation
Aggregation level ≤ 5%
Immunogen
Unknown
Antigen Distribution
The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Buffer
ICH3002
Uniprot
P01903;P01903;P01911;P01903;P01911;
Shipping Conditions
Blue ice
Background
HLA-DR is a major MHC class II molecule central to antigen presentation, immune activation, and transplantation research. Clone L243 is a mouse IgG2a monoclonal antibody recognizing human HLA-DR, validated for flow cytometry and ELISA, and supplied here as an Fc-biotinylated conjugate for streptavidin-based assays. Anti-HLA-DR clone L243 is provided in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram to gram quantities to serve bulk and high-throughput laboratories. Researchers value L243 for consistent, reliable detection of HLA-DR across immunology studies, with this reagent offered for research use only.
Other Names
Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic
Clone
L243
Specificity
Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Applications
Flow Cytometry, ELISA
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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