Bulk Anti-Human CD8 (UCHT-4) Antibody

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SKU

ICH1005

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$390.00

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Bulk Anti-Human CD8 (UCHT-4) Antibody

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Concentration	1.0 - 5.0 mg/ml
Isotype	Mouse IgG2a
Host	Mouse
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Applications	Flow Cytometry, Western Blot, Immunoprecipitation, Functional Assays, IHC, Immunofluorescence, ELISA
Storage	anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin	<1.0 EU/mg as determined by the LAL method
Purity	>95% by SDS-PAGE and HPLC
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purification Method	This monoclonal antibody was purified using Protein A
Specificity	Anti-CD8 In Vivo Antibody - Low Endotoxin (UCHT-4) recognizes Human CD8. Anti-Human CD8 recognizes a T-cell glycoprotein cell surface complex (Mr 32 kDa) which defines the cytotoxic/suppressor population of mature T-lymphocytes. The CD8 complex interacts
Species Reactivity	Human
Target	CD8
Shipping Conditions	Blue ice
background	Anti-CD8 may be used in studies of immunoregulation and T-lymphocyte mediated suppression, autoimmune disorders, immunodeficiency states and acute lymphoblastic leukemia and lymphoma.
clone	UCHT-4
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml
Antigen Distribution	The CD8 antigen is expressed on approximately 19-48% of normal human peripheral blood lymphocytes and > 90% of normal thymocytes. It is also present on a subset of NK cells. Subjects infected with HIV have been shown to exhibit increased levels of CD8+ ly
Aggregation	Aggregation level ≤ 5%
Antibodies against the same target	Anti-CD8 In Vivo Antibody - Low Endotoxin [YTS-169] (ICH1043), Anti-CD8 In Vivo Antibody - Ultra Low Endotoxin [YTS-169] (ICH1043UL)