CAR Modulation Antibody Panel

This antibody panel consists of the following :
ICH5024-0.1mg        Muromonab Biosimilar
ICH5023-0.1mg        Theralizumab Biosimilar
ICH5015-0.1mg        Urelumab Biosimilar
ICH4029-0.1mg        Pembrolizumab Biosimilar
ICH4018-0.1mg        Atezolizumab Biosimilar
ICH5077-0.1mg        Fresolimumab Biosimilar

 

Concentration

1.0 mg/ml

Isotype
Mouse IgG2a CH1 + Human IgG1 CH2 + CH3 – Mouse Kappa (muromonab), Human IgG4 (theralizumab), Human IgG1 (urelumab), Human IgG4 kappa (pembrolizumab), Human IgG1 kappa (atezolizumab), Human IgG4 S228P kappa (fresolimumab).

Target
CD3, CD28, 4-1BB, PD-1, PD-L1, TGF-B

Specificity
Human

Purification Method
All the monoclonal antibodies in this panel were purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Formulation

95% by SDS-PAGE

Purity

95% by SDS-PAGE

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method.

Storage
Stable for at least one week when stored sterile at 2–8°C. For long-term storage, aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid repeated freeze–thaw cycles.

Applications
Functional assays.

Application Notes
These antibodies are for research use only (RUO): they are not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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