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Anti-Human HLA-DP (B7/21) Antibody: Fc Biotinylated
$200.00 - $1,700.00
Anti-Human HLA-DP (B7/21) Antibody: Fc Biotinylated
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
HLA-DP
Concentration
1.0 mg/ml
Isotype
Mouse IgG3
Host
Mouse
Aggregation
Aggregation level ≤ 5%
Immunogen
Unknown
Antigen Distribution
The HLA-DP antigen is present on approximately 10% of normal peripheral blood lymphocytes but not on resting peripheral T-lymphocytes. HLA-DP is present in low density on peripheral blood monocytes and mitogen-stimulated T-lymphoblasts. Anti-HLA-DP reacts
Buffer
ICH3002
Uniprot
P20036
Shipping Conditions
Blue ice
Background
HLA-DP is an MHC class II molecule that presents antigenic peptides to CD4 T cells and contributes to transplantation and autoimmunity research. Clone B7/21 is a mouse IgG3 monoclonal antibody recognizing human HLA-DP, validated for flow cytometry and ELISA, and this version is supplied as an Fc-biotinylated conjugate for streptavidin-based detection. Anti-HLA-DP clone B7/21 is provided in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram to gram quantities for bulk and high-throughput laboratories. Researchers rely on B7/21 for consistent HLA class II studies, with this reagent offered for research use only.
Other Names
HLA-DP Monomorphic
Clone
B7/21
Specificity
Anti-HLA-DP In Vivo Antibody - Low Endotoxin (B7/21) recognizes a (Mr 26-34 kDa) class II major histocompatibility complex (MHC) antigen. The antibody recognizes a monomorphic determinant present on cells expressing DP1, DP2, DP3, DP4 and DP5.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Applications
Flow Cytometry, ELISA
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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