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Human IgG1 Isotype Control P329G/E356D/M358L
$315.00 - $5,200.00
Human IgG1 Isotype Control P329G/E356D/M358L
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (P329G/E356D/M358L)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Combining the P329G mutation that disrupts Fcγ receptor contact with the E356D and M358L allotype substitutions, this human IgG1 control is raised against hen egg lysozyme and thus has no mammalian specificity. It serves as a matched negative control for setting background levels and gating in functional and flow cytometry experiments, ensuring observed effects derive from genuine antigen binding rather than the IgG1 scaffold. Supplied in a low-endotoxin format suitable for in vivo use, it is produced in scalable milligram to gram quantities for bulk and high-throughput research. The antibody is non-therapeutic and intended for research use only.
Specificity
Human IgG1 with a P329G/E356D/M358L mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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