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Bulk Anti-Human CD11a (38) Antibody
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Bulk Anti-Human CD11a (38) Antibody
| Concentration | 1.0 - 5.0 mg/ml |
|---|---|
| Isotype | Mouse IgG2a |
| Host | Mouse |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Flow Cytometry, Western Blot, IHC (Frozen), Immunofluorescence, Immunoprecipitation |
| Storage | anti-CD11a In Vivo Antibody - Low Endotoxin (38) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein A |
| Specificity | Anti-CD11a In Vivo Antibody - Low Endotoxin (38) recognizes Human CD11a. Anti-Human CD11a (Anti-LFA-1a) recognizes the (Mr 175 kDa) a chain of the leukocyte function associated antigen-1 (LFA-1). The leukocyte integrin LFA-1 is a member of a family of het |
| Species Reactivity | Human |
| Target | CD11a |
| Shipping Conditions | Blue ice |
| background | Anti-CD11a may be used to study a variety of biological phenomena related to the function of cell adhesion molecules. This antibody may be used to study transplantation rejections and to assist in characterizing lymphomas and leukemias. |
| Other names | LFA-1 alpha, LFA-1A, Integrin alpha-L, ITGAL |
| clone | 38 |
| UniProt | P20701 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | The CD11a antigen is present on most leukocytes and plays a vital role in cellular immune responses which require adhesion. Lymphocyte activation via the T-cell antigen receptor (TCR) up-regulates LFA-1 function. The absence of LFA-1A or B may induce the |
| Immunogen | Unknown |
| Aggregation | Aggregation level ≤ 5% |
| Antibodies against the same target | Anti-CD11a In Vivo Antibody - Low Endotoxin [FD441.8] (ICH1047), Anti-CD11a In Vivo Antibody - Low Endotoxin [I21/7] (ICH1048) |
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