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Setrusumab Biosimilar - Research Grade
$710.00 - $6,900.00
Setrusumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
SOSTï؟½
Concentration
5mg/ml
Isotype
IgG2 - lambda
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q9BQB4
Shipping Conditions
Blue ice
Background
Sclerostin (SOST) is a negative regulator of Wnt signaling in bone that suppresses osteoblast activity, making it central to skeletal and bone-formation research. Offered here is a non-therapeutic, unconjugated analog of setrusumab, a recombinant anti-sclerostin monoclonal antibody supplied for research use only. It is manufactured to in vivo standards in a low-endotoxin format and made in scalable milligram to gram quantities for heavy-usage laboratories. The antibody suits sclerostin-neutralization functional assays, in vitro osteoblast-signaling screens, and in vivo models of bone formation and remodeling. Its reproducible formulation and scalable volumes support standardized results in bulk research.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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