Sabatolimab Biosimilar - Research Grade

Human

Tim-3

5mg/ml

Human IgG4 S228P Kappa

CHO cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human Tim-3. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sabatolimab.

Blue ice

Tim-3 (HAVCR2) is a co-inhibitory receptor marking exhausted T cells and is actively pursued as a checkpoint target in oncology and chronic-infection research. Presented here is a research-grade anti-human Tim-3 recombinant monoclonal antibody, an unconjugated, non-therapeutic analog of sabatolimab built on a human IgG4 (S228P) framework and supplied for research use only (RUO). Manufactured to in vivo quality with low endotoxin throughout, it is produced in scalable milligram (mg) to gram (g) batches for high-throughput and heavy-usage settings. Typical applications include receptor-blocking and functional assays, T-cell exhaustion studies, and in vivo preclinical tumour models.

Q8TDQ0

ICH3002

https://www.imgt.org/mAb-DB/