Talquetamab Biosimilar - Research Grade

Human

CD3 + GPRC5D

5mg/ml

Human IgG4 (S228P/F234A/L235A)-kappa

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects CD3xGPRC5D

Blue ice

GPRC5D is an orphan receptor over-expressed on malignant plasma cells, while CD3 enables T-cell engagement, making the pair a focus of multiple-myeloma research. This bispecific reagent is an unconjugated, non-therapeutic analog of talquetamab that bridges CD3 and GPRC5D and is supplied for research use only (RUO). It is manufactured to in vivo standards, carries low endotoxin, and is available in scalable milligram (mg) to gram (g) quantities for high-throughput laboratories. Researchers apply it in functional assays, T-cell-redirected cytotoxicity studies, defined controls, and in vivo myeloma models that demand reproducible, well-characterised bispecific reagents.

JNJ-64407564;CD3e, CD3 epsilon;G protein-coupled receptor class C group 5 member D

P07766;Q9NZD1

ICH3002

https://www.imgt.org/mAb-DB/