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Patritumab Biosimilar - Research Grade
$315.00 - $19,890.00
Patritumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
HER3
Concentration
5mg/ml
Isotype
Human IgG1 Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects HER3
Shipping Conditions
Blue ice
Background
Human epidermal growth factor receptor 3 (HER3/ERBB3) is a signalling co-receptor that drives resistance in many carcinomas, a recurring target in oncology research. This recombinant anti-human HER3 monoclonal is an unconjugated, non-therapeutic analog of patritumab, supplied for research use only (RUO). Manufactured to in vivo standards with low endotoxin, it is offered in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Applications include functional assays, receptor-blockade and signalling studies, reproducible controls, and in vivo tumour models, providing the lot-to-lot consistency expected by heavy-usage oncology research programmes.
Other Names
U3-1287;ERBB3,receptor tyrosine-protein kinase erbB-3, HER3
Uniprot
P21860
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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