Olokizumab Biosimilar - Research Grade

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SKU
ICH5170
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$315.00 - $19,890.00

Olokizumab Biosimilar - Research Grade

Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Species Reactivity
Human
Target
IL-6
Concentration
5mg/ml
Isotype
Human IgG4 S228P Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human IL-6
Shipping Conditions
Blue ice
Background
Interleukin-6 (IL-6) is a pleiotropic cytokine that coordinates inflammation, acute-phase responses, and immune cell behaviour, and is among the most studied targets in inflammatory disease research. Our anti-human IL-6 recombinant monoclonal is an unconjugated, non-therapeutic analog of olokizumab, supplied strictly for research use only (RUO). Produced to in vivo standards, the low-endotoxin formulation is delivered in scalable milligram (mg) to gram (g) batches for heavy-usage and high-throughput facilities. It acts as a neutralising and control reagent across in vitro cytokine assays, ex vivo signalling studies, and in vivo inflammatory models, offering reliable consistency across large experimental campaigns.
Uniprot
P05231
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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