Istiratumab Biosimilar - Research Grade

Human

IGF1R + Her3

5mg/ml

Human IgG1 (E356D/M358L)-kappa-ScFv

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects IGF1RxHer3

Blue ice

Insulin-like growth factor 1 receptor (IGF1R) and HER3 are convergent drivers of proliferative signalling, and their co-targeting is a theme in oncology research. This bispecific reagent is an unconjugated, non-therapeutic analog of istiratumab that engages both IGF1R and HER3, supplied for research use only (RUO). Produced to in vivo standards with low endotoxin, it is offered in scalable milligram (mg) to gram (g) quantities for high-throughput laboratories. Use it in functional assays, dual-receptor-blockade and signalling studies, reproducible controls, and in vivo tumour models, relying on its consistency for the large datasets typical of bispecific oncology research.

insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221;receptor tyrosine-protein kinase erbB-3, HER3

P08069;P21860

ICH3002

https://www.imgt.org/mAb-DB/