Ganitumab Biosimilar - Research Grade

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SKU
ICH5216
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$315.00 - $19,890.00

Ganitumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
IGF1R
Concentration
5mg/ml
Isotype
Human IgG1 (E356D/M358L)-kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects IGF1R
Shipping Conditions
Blue ice
Background
Insulin-like growth factor 1 receptor (IGF1R) is a tyrosine-kinase receptor that promotes survival and proliferation across many cancers, a recurring target in oncology research. This recombinant anti-human IGF1R monoclonal is an unconjugated, non-therapeutic analog of ganitumab, supplied for research use only (RUO). It is manufactured to in vivo standards with low endotoxin and produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Applications include functional assays, receptor-blockade and signalling studies, reproducible controls, and in vivo tumour models, with the lot-to-lot consistency that heavy-usage oncology programmes require.
Other Names
insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221_AMG 479
Uniprot
P06213;P08069;P08069
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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