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Human IgG4 Isotype Control S228P (Lambda1)
$315.00 - $5,200.00
Human IgG4 Isotype Control S228P (Lambda1)
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG4 (S228P)-Lambda1
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG4 (S228P) isotype control with a lambda1 light chain provides a matched negative reference for studies that use IgG4-lambda format antibodies. The S228P hinge stabilisation prevents Fab-arm exchange, while the control's lack of relevant binding lets it set the background and gating thresholds that distinguish specific engagement from scaffold signal in functional and cytometric assays. It is formulated low in endotoxin and validated for in vivo administration, and manufactured at scalable milligram to gram quantities to support high-throughput and bulk laboratories. The antibody is non-therapeutic and intended strictly for research use only.
Specificity
Human IgG4 with a S228P (Lambda1) mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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