Cadonilimab Biosimilar - Research Grade

Human

PD-1 + CTLA-4

5mg/ml

Human IgG1-kappa-(scFv - heavy - lambda2)

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects PD-1xCTLA-4

Blue ice

PD-1 and CTLA-4 are complementary inhibitory checkpoints whose combined targeting is a central strategy in immuno-oncology research. This bispecific reagent is an unconjugated, non-therapeutic analog of cadonilimab that simultaneously engages PD-1 and CTLA-4 and is supplied strictly for research use only (RUO). Produced to in vivo standards with low endotoxin, it is offered in scalable milligram (mg) to gram (g) quantities for heavy-usage and high-throughput laboratories. It is useful in functional assays, dual-checkpoint-blockade and T-cell-activation studies, reproducible controls, and in vivo tumour models, providing the consistency required for comparative and combination immuno-oncology experiments.

AK-104,AK104;cytotoxic T-lymphocyte-associated protein 4, CD152;programmed cell death 1, PD1, PD-1, CD279,PDCD1

Q15116;P16410

ICH3002

https://www.imgt.org/mAb-DB/