Enfortumab Biosimilar - Research Grade

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SKU
ICH5070
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$315.00 - $19,890.00

Enfortumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
Nectin-4
Concentration
5mg/ml
Isotype
Human IgG1 Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human Nectin-4. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Enfortumab
Shipping Conditions
Blue ice
Background
Nectin-4 is an adhesion molecule over-expressed on urothelial and other carcinomas and a validated target for antibody-based tumour delivery in oncology research. This research-grade antibody is an unconjugated, non-therapeutic analog of enfortumab recognising human Nectin-4 and validated for functional assays. It is intended for research use only, purified to a low-endotoxin standard suitable for in vivo studies, and produced in scalable milligram to gram quantities for high-throughput laboratories. Applications include tumour-antigen binding and internalisation assays, in vitro screening, in vivo tumour models, ADC development, and biologics characterisation.
Uniprot
Q96NY8
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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