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Mirzotamab Biosimilar - Research Grade
$710.00 - $6,900.00
Mirzotamab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CD276ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q5ZPR3
Shipping Conditions
Blue ice
Background
B7-H3 (CD276) is an immune-checkpoint molecule broadly overexpressed on solid tumors yet limited on normal tissue, making it an attractive antigen in cancer immunology. We offer an unconjugated, non-therapeutic analog of mirzotamab as a recombinant human IgG1 kappa antibody against CD276, strictly for research use only (RUO). The reagent is purified to low endotoxin so it can be deployed in vivo, and it is produced in scalable milligram-to-gram lots that accommodate heavy-usage and high-throughput laboratories. It supports binding and functional assays, in vitro screening, ADCC studies, preclinical tumor models, and antibody-drug-conjugate development.
Other Names
B7-H3, B7H3
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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