Lenzilumab Biosimilar - Research Grade

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SKU
ICH5166
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$315.00 - $19,890.00

Lenzilumab Biosimilar - Research Grade

Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Species Reactivity
Human
Target
CSF2
Concentration
5mg/ml
Isotype
Human IgG1 Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human CSF2
Shipping Conditions
Blue ice
Background
Granulocyte-macrophage colony-stimulating factor (CSF2/GM-CSF) is a myeloid growth factor central to inflammation and emergency haematopoiesis, and a frequent subject of immunology research. Our anti-human CSF2 recombinant monoclonal is an unconjugated, non-therapeutic analog of lenzilumab, supplied for research use only (RUO). Engineered to in vivo quality standards, the low-endotoxin preparation is manufactured in scalable milligram (mg) to gram (g) batches for heavy-usage and high-throughput laboratories. Researchers use it in functional assays as a cytokine-neutralisation and control reagent, scaling readily from in vitro screening through to in vivo models of inflammatory and myeloid disease without compromising reproducibility.
Uniprot
P04141
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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