Crizanlizumab Biosimilar - Research Grade

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SKU
ICH5300
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$315.00 - $19,890.00

Crizanlizumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
SELP
Concentration
5mg/ml
Isotype
Human IgG2 (P189T/V282M/K322A/S378A)-kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P16109
Shipping Conditions
Blue ice
Background
P-selectin (SELP) is a cell-adhesion molecule that mediates leukocyte and platelet rolling and is studied across inflammation, thrombosis, and vaso-occlusive disease. Offered as an unconjugated, non-therapeutic analog of crizanlizumab, this research-grade anti-human P-selectin recombinant monoclonal antibody is for research use only (RUO). It is manufactured to in vivo standards, formulated for low endotoxin, and supplied in scalable milligram (mg) to gram (g) quantities for high-throughput and heavy-usage laboratories. Applications include adhesion-blocking assays, in vitro functional screening, and in vivo inflammation and thrombosis models requiring a reproducible reagent.
Other Names
SelG1,SEG101,selectin P, CD62
Specificity
Detects human SELP
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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