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Human IgG1 Isotype Control N297A/E356D/M358L
$315.00 - $5,200.00
Human IgG1 Isotype Control N297A/E356D/M358L
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (N297A/E356D/M358L)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG1 isotype control combines the aglycosylating N297A mutation, which removes Fc glycan-dependent effector function, with the E356D and M358L allotype changes, and it is raised against hen egg lysozyme so it has no mammalian specificity. As a matched negative control it anchors background and gating measurements, helping researchers separate genuine target engagement from scaffold or Fc effects across flow cytometry and functional studies. The antibody is provided low in endotoxin and suitable for in vivo use, and it is produced at scalable milligram to gram quantities for bulk and high-throughput laboratories. Research use only, non-therapeutic.
Specificity
Human IgG1 with a N297A/E356D/M358L mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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