Human IgG1 Isotype Control LALA/E356D/M358L

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SKU
ICH2254LALAEDML
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$315.00 - $5,200.00

Human IgG1 Isotype Control LALA/E356D/M358L

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (L234A/L235A/E356D/M358L)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Combining the LALA effector-silencing mutations with the E356D and M358L allotype substitutions, this human IgG1 targets hen egg lysozyme and thus serves purely as a matched negative control in mammalian research. Researchers use it alongside engineered antibodies to benchmark non-specific signal, calibrate gates, and verify that biological effects arise from genuine target binding rather than the antibody scaffold. It is well suited to flow cytometry, functional assays, and in vivo model controls. The preparation is low in endotoxin and validated for in vivo administration, and it is produced in scalable milligram to gram quantities for heavy-usage laboratories. Strictly for research use only.
Specificity
Human IgG1 with a LALA/E356D/M358L mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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