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Anti-Mouse IL-6 (MP5-20F3) In Vivo Antibody - Low Endotoxin
$230.00 - $1,320.00
Anti-Mouse IL-6 (MP5-20F3) In Vivo Antibody - Low Endotoxin
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Mouse
Target
Interleukin-6
Concentration
1.0 mg/ml
Isotype
Rat IgG1
Host
Rat
Aggregation
Aggregation level ≤ 5%
Buffer
ICH3002
Uniprot
P08505
Shipping Conditions
Blue ice
Background
Interleukin-6 is a pleiotropic cytokine driving inflammation, acute-phase responses, and immune regulation in mice and humans alike. Clone MP5-20F3 is a rat IgG1 monoclonal antibody against mouse IL-6, validated for ELISA capture, ELISPOT, functional assays, in vivo studies, and neutralization. Anti-mouse IL-6 clone MP5-20F3 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities to support bulk and high-throughput laboratories. With reliable lot-to-lot consistency, MP5-20F3 is a dependable reagent for murine cytokine and inflammation research, offered for research use only.
Other Names
Interleukin-6, IL6, Anti-Mouse IL6, Anti-Mouse IL-6, BCSF
Clone
MP5-20F3
Specificity
Clone MP5-20F3 recognizes an epitope on mouse IL-6.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Storage
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Applications
ELISA Capture, ELISPOT, Functional Assays, in vivo, Neutralization
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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