Ivonescimab Biosimilar - Research Grade

Human

VEGFAxPD-1

>1mg/ml

Human IgG1(L234A/L235A)-kappa

CHO Cells

https://www.imgt.org/mAb-DB/

ICH3002

Blue Ice

VEGF-A and PD-1 represent two complementary axes in tumor angiogenesis and immune evasion, and their simultaneous targeting is an active strategy in immuno-oncology research. This research-grade, non-therapeutic biosimilar analog of ivonescimab is a bispecific recombinant human IgG1 antibody engineered to bind both VEGF-A and PD-1, supplied for research use only (RUO). It is purified to a low-endotoxin standard suitable for in vivo studies and produced in scalable milligram to gram quantities for high-throughput and bulk laboratories. The reagent supports dual-target binding assays, in vitro angiogenesis and checkpoint screening, control work, and preclinical tumor models.

AK112,AK-112,AK 112

Ion Exchange Chromatography

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Functional Assays

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.