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Anti-Mouse CD70 (TAN 1-7) In Vivo Antibody - Low Endotoxin
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Bulk anti-CD70 In Vivo Antibody - Low Endotoxin (TAN1-7)
Product Benefits:
ichorbio's anti- CD70 In Vivo Antibody - Low Endotoxin (TAN1-7) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from Bio X Cell at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.5EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.
Target:
CD70
Other Names:
CD27 Ligand, TNFSF7, Tumor Necrosis Factor Ligand 8A, CD27L, CD70 Antigen.
Clone:
TAN1-7
Size:
ichorbio's TAN1-7 in vivo antibody is available in the following bulk sizes: 1mg, 5mg, 25mg, 50mg and 100mg ichorbio regularly manufactures multi-gram amounts of our anti-CD70 TAN1-7 clone - please contact us for pricing.
Isotype:
Rat IgG2a k
Uniprot:
Host:
Rat
Species Reactivity:
Mouse
Specificity:
Clone TAN 1-7 recognizes mouse CD70.
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
CD70 is expressed on activated T Cells, B Cells, and dendritic cells.
Background:
CD70, a cytokine and also known as CD27 ligand, is a member of the tumor necrosis family. As a cytokine, CD70 plays a role in regulating B cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. Non-small cell lung cancer research has shown that CD70 increases the survivability of tumor cells and T cells by signaling through its receptor CD27.
Immunogen:
Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
Concentration:
>2.0 mg/ml
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
IMPACT Pathogen Test:
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp. Mycoplasma pulmonis Sendai virus Mouse hepatitis virus Pneumonia virus of mice Minute virus of mice Mouse parvovirus (MPV1-5) Theiler’s murine encephalomyelitis virus Murine norovirus Reovirus 3 Mouse rotavirus Ectromelia virus Lymphocytic choriomeningitis virus Polyoma virus Lactate dehydrogenase-elevating virus Mouse adenovirus (MAD1, MAD2) Mouse cytomegalovirus K virus Mouse thymic virus Hantaan virus Corynebacterium bovis Corynebacterium spp. (HAC2)
Storage:
This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.
Applications:
ELISA, Flow Cytometry, Immunofluorescence, Blocking
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only.
Alternative Names:
- CD 27L antibody
- CD 70 antibody
- CD27 L antibody
- CD27 LG antibody
- CD27 ligand antibody
- CD27-L antibody
- CD27L antibody
- CD27LG antibody
- CD70 antibody
- CD70 antigen antibody
- CD70 molecule antibody
- CD70_HUMAN antibody
- Ki 24 antigen antibody
- Ki24 antigen antibody
- Surface antigen CD70 antibody
- TNFSF 7 antibody
- TNFSF7 antibody
- Tumor necrosis factor (ligand) superfamily, member 7 antibody
- Tumor necrosis factor ligand superfamily member 7 antibody
| Concentration | >2.0 mg/ml |
|---|---|
| Isotype | Rat IgG2a k |
| Host | Rat |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | ELISA, Flow Cytometry, Immunofluorescence, Blocking |
| Storage | This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 ≤ 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free |
| Purification Method | This monoclonal antibody was purified using Protein G |
| Specificity | Clone TAN 1-7 recognizes mouse CD70. |
| Species Reactivity | Mouse |
| Target | CD70 |
| Shipping Conditions | Blue ice |
| background | CD70, a cytokine and also known as CD27 ligand, is a member of the tumor necrosis family. As a cytokine, CD70 plays a role in regulating B cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. Non-small cell lung cance |
| Other names | CD27 Ligand, TNFSF7, Tumor Necrosis Factor Ligand 8A, CD27L, CD70 Antigen |
| clone | TAN1-7 |
| UniProt | O55237 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | CD70 is expressed on activated T Cells, B Cells, and dendritic cells. |
| Immunogen | Recombinant mouse CD70 (extracellular domain, aa residues 41-195). |
| Aggregation | Aggregation level ≤ 5% |
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