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Uprevstobart Biosimilar - Research Grade
$710.00 - $6,900.00
Uprevstobart Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
NT5Eï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P21589
Shipping Conditions
Blue ice
Background
CD73 (NT5E) is an ecto-5'-nucleotidase that generates immunosuppressive adenosine in the tumor microenvironment, a pathway under intense study in cancer immunology. Provided as an unconjugated, non-therapeutic analog of uprevstobart, this recombinant human IgG1 antibody targets NT5E and is supplied for research use only (RUO). It is purified to a low-endotoxin level suitable for in vivo experiments and produced in scalable milligram-to-gram quantities to meet the throughput needs of bulk laboratories. Researchers apply it in enzyme-blocking and binding assays, in vitro adenosine-pathway screening, control work, and preclinical immuno-oncology models.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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