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Lucatumumab Biosimilar - Research Grade
$315.00 - $19,890.00
Lucatumumab Biosimilar - Research Grade
Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Species Reactivity
Human
Target
CD40
Concentration
5mg/ml
Isotype
Human IgG1 (S131A)-Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human CD40
Shipping Conditions
Blue ice
Background
CD40 is a co-stimulatory receptor of the TNFR superfamily expressed on antigen-presenting cells, where it governs immune activation and is a key target in immuno-oncology research. Offered here is a research-grade anti-human CD40 recombinant monoclonal antibody, an unconjugated, non-therapeutic analog of lucatumumab, supplied for research use only (RUO). Manufactured to in vivo standards with low endotoxin, it is provided in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. The reagent supports CD40-signalling and functional assays, antigen-presenting-cell studies, in vitro screening, and in vivo preclinical immunology models.
Other Names
CD40, Bp50, CDW40, TNFRSF5, p50, CD40 (protein), CD40 molecule
Uniprot
P25942
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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