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Page 4 - in vivo research
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June 17, 2021
We have provided a pdf version of this document so that you can easily print out the specific pages you want to read in more detail (please be mindful before printing the whole article).
Basic things to remember when injecting mice
- Use a new needle for each injected animal. Consider needle-free injectors if possible...
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May 29, 2021
Thinking about a career in the life sciences? ichorbio has done extensive research on a range of careers within life science - in the USA, UK, France and Germany to help you understand the sorts of salaries you will be commanding in 2023. Our research shows that geography will have the biggest difference on your take-home pay.
Table of Contents
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May 06, 2021
Advancing Translational Research through Optimized Animal Models, Predictive Strategies, and Emerging Technologies
Abstract:
Translational research serves as a critical bridge between basic science discoveries and clinical applications, with animal models playing a pivotal role in this process. This article explores the importance of animal models in drug development...
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April 24, 2021
Contents
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February 18, 2021
Exosomal PD-L1 (exoPD-L1) has recently received significant attention as a biomarker predicting immunotherapeutic responses involving the PD1/PD-L1 pathway. However, current technologies for exosomal analysis rely primarily on bulk measurements that do not consider the heterogeneity found within exosomal subpopulations.
A new study presents a nanoscale cytometry platform called NanoEPIC, enabling phenotypic sorting and exoPD-L1 profiling from...
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November 10, 2020
Introduction
The...
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September 20, 2020
Recent research on the effects of the rare GAALIE mutation when present in the Fc domain of antibodies provides intriguing insights that may inform engineering of oncology therapeutics. Antibody Fc domains play a central role in eliciting anti-tumor immune responses, and customizing this region is an important strategy for enhancing cancer immunotherapy. Studies in 2023 exploring how the GAALIE mutation impacts Fc activities point to molecular mechanisms...
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July 15, 2020
Updated report: Sequences from 745 antibodies and fusion proteins
Updated 15th February 2023:
In the following links you will find two spreadsheets containing antibody sequences for 745 therapeutic antibodies & fusion proteins.
We’ve created them as a resource for the scientific community – we hope that it will help you to design new and improved therapeutics at a faster rate.
Our spreadsheet includes antibody...
