Quavonlimab Biosimilar - Research Grade

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SKU
ICH5794
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Quavonlimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CTLA4ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P09793;P16410
Shipping Conditions
Blue ice
Background
CTLA-4 is a primary inhibitory checkpoint that downregulates T-cell activation, making it a cornerstone of immuno-oncology research. This unconjugated human IgG1 kappa antibody is a non-therapeutic analog of quavonlimab, expressed in CHO cells against human CTLA4. Supplied for research use only, it is purified to a low-endotoxin standard suitable for in vivo studies and offered in scalable milligram (mg) to gram (g) quantities for bulk, high-throughput laboratories. It is a dependable reagent for checkpoint-blockade functional assays, T-cell activity studies, ADCC investigations, and preclinical tumor-immunity models. It delivers the consistency that bulk-consuming research programs require.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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