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Prezalumab Biosimilar - Research Grade
$315.00 - $19,890.00
Prezalumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
B7H2
Concentration
5mg/ml
Isotype
Human IgG2 (S378A)-Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects B7H2
Shipping Conditions
Blue ice
Background
B7-H2 (ICOSLG) is a co-stimulatory ligand that engages ICOS to shape T-cell help, of interest across immunology and autoimmune research. Supplied as an unconjugated, non-therapeutic analog of prezalumab, this recombinant anti-human B7H2 antibody is for research use only (RUO). It is manufactured to in vivo standards, presents low endotoxin, and is available in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. The reagent supports functional assays, co-stimulation-blockade and T-cell studies, reproducible controls, and in vivo models of immune regulation, delivering dependable lot-to-lot consistency for high-volume immunology programmes.
Other Names
inducible T-cell co-stimulator ligand, B7H2, B7-H2, ICOS-L, B7-related protein 1, B7RP1, B7RP-1, B7 homolog 2, B7 homologue 2, GL50, KIAA0653, CD275
Uniprot
O75144
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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