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Onartuzumab Biosimilar - Research Grade
$315.00 - $19,890.00
Onartuzumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
MET
Concentration
5mg/ml
Isotype
Human Fab - G1 - kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects MET
Shipping Conditions
Blue ice
Background
The hepatocyte growth factor receptor MET drives invasive growth and is a frequent contributor to therapy resistance in solid-tumour research. This monovalent Fab reagent is an unconjugated, non-therapeutic analog of onartuzumab directed against MET, supplied for research use only (RUO). It is produced to in vivo standards, carries low endotoxin, and is available in scalable milligram (mg) to gram (g) quantities for heavy-usage and high-throughput laboratories. Researchers apply it in functional assays, receptor-blockade and downstream-signalling studies, defined controls, and in vivo tumour models that benefit from a monovalent, reproducible reagent format.
Other Names
MetMAb,OA-5D5,OA5D5,PRO 143966;met proto-oncogene, hepatocyte growth factor (HGF) receptor, HGFR, scatter factor (SF) receptor, HGF/SF receptor, receptor tyrosine-protein kinase c-met, papillary renal cell carcinoma 2, RCCP2
Uniprot
P08581
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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