Ifinatamab Biosimilar - Research Grade

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SKU
ICH5204
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$315.00 - $19,890.00

Ifinatamab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
B7-H3
Concentration
5mg/ml
Isotype
Human IgG1 Kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects B7-H3
Shipping Conditions
Blue ice
Background
B7-H3 (CD276) is an immune-modulatory molecule broadly over-expressed on solid tumours and a prominent target in cancer-targeting research. Supplied as an unconjugated, non-therapeutic analog of ifinatamab, this recombinant anti-human B7-H3 monoclonal is for research use only (RUO). It is manufactured to in vivo standards with low endotoxin and produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Researchers use it in functional assays, tumour-binding and internalisation studies, ADC-development workflows, reproducible controls, and in vivo solid-tumour models, relying on its lot-to-lot consistency for large, heavy-usage experimental campaigns.
Other Names
MABX-9001a;B7H3, B7-H3, B7-related protein 2, B7RP2, B7RP-2, B7 homolog 3, B7 homologue 3,CD276
Uniprot
Q5ZPR3
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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