Mepolizumab Biosimilar - Research Grade

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SKU
ICH5677
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Mepolizumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
IL5ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P05113
Shipping Conditions
Blue ice
Background
Interleukin-5 is the principal cytokine controlling eosinophil maturation and survival, making it a longstanding target in asthma and eosinophilic-disease research. This anti-human IL5 recombinant monoclonal antibody (IgG1, kappa) is an unconjugated, non-therapeutic analog of mepolizumab provided for research use only (RUO). It is formulated to a low-endotoxin standard appropriate for in vivo studies and manufactured at scalable milligram-to-gram quantities so bulk and high-throughput laboratories never face shortages. The reagent serves effectively as a neutralizing control and active tool in cytokine-blockade assays, in vitro eosinophil and binding screening, and preclinical in vivo models of allergic and eosinophilic inflammation.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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