Letaplimab Biosimilar - Research Grade

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SKU
ICH5251
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$710.00 - $19,500.00
Delivery Time : 4 weeks

Letaplimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
CD47
Concentration
5mg/ml
Isotype
Human IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH2872
Uniprot
Q08722;Q08722;Q61735;P97829;Q08722;Q61735;P97829;;Q61735
Shipping Conditions
Blue ice
Background
CD47 is a widely expressed 'don't-eat-me' signal that suppresses macrophage phagocytosis, a central target across innate-immunity and oncology research. This recombinant anti-human CD47 monoclonal is an unconjugated, non-therapeutic analog of letaplimab, supplied for research use only (RUO). Manufactured to in vivo standards with low endotoxin, it is offered in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Applications include functional assays, phagocytosis and SIRPα-blockade studies, reproducible controls, and in vivo tumour-immunity models, providing the consistency required for extended, heavy-usage innate-immunity research.
Other Names
CD47, IAP, MER6, OA3, CD47 molecule, integrin associated protein
Specificity
Detects human CD47
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
4 weeks
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