Encelimab Biosimilar - Research Grade

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SKU
ICH5524
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Encelimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
LAG3ï؟½
Concentration
5mg/ml
Isotype
IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P18627
Shipping Conditions
Blue ice
Background
LAG-3 (LAG3) is an inhibitory immune checkpoint receptor expressed on activated T cells, where it restrains effector function and contributes to T-cell exhaustion. Targeting LAG3, this research-grade anti-human recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of encelimab supplied strictly for research use only (RUO). Manufactured under rigorous in vivo standards, the ultra-pure, low-endotoxin preparation is available in scalable milligram (mg) to gram (g) quantities to support heavy-usage, high-throughput laboratories. It serves checkpoint-blockade research, in vitro receptor-ligand and T-cell functional assays, in vivo tumor immunology models, and biologics characterization, functioning as a consistent control reagent throughout preclinical pipelines.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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