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Ado-Trastuzumab Emtansine Biosimilar - Research Grade
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Ado-Trastuzumab Emtansine Biosimilar - Research Grade
| Species Reactivity | Human |
|---|---|
| Target | HER2 |
| Concentration | 1.0 - 5.0 mg/ml |
| Isotype | Human IgG1 |
| Host | Humanized |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine. |
| Shipping Conditions | Blue ice |
| background | Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese |
| Other names | Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu |
| UniProt | P04626 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Sequence | https://www.imgt.org/mAb-DB/ |
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