Tremelimumab Biosimilar - Research Grade

Human

CTLA-4

5mg/ml

Human IgG2 kappa

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human CTLA-4

Blue ice

Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is an inhibitory checkpoint that restrains early T-cell activation and a foundational target in cancer immunology research. Supplied as an unconjugated, non-therapeutic analog of tremelimumab, this recombinant anti-human CTLA-4 monoclonal is for research use only (RUO). It is produced to in vivo standards with low endotoxin and available in scalable milligram (mg) to gram (g) lots that fit heavy-usage and high-throughput workflows. The reagent supports functional assays, checkpoint-blockade and T-cell co-stimulation studies, reproducible controls, and in vivo immuno-oncology models, providing the lot consistency needed for comparative and combination experiments.

P16410

ICH3002

https://www.imgt.org/mAb-DB/