Ponsegromab Biosimilar - Research Grade

Human

GDF15

5mg/ml

Human IgG1 (L234A/L235A/G237A/KDel)-Kappa

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human GDF15

Blue ice

Growth differentiation factor 15 (GDF15) is a stress-responsive cytokine implicated in cachexia and metabolic signalling, and a growing focus of metabolism research. Our anti-human GDF15 recombinant monoclonal is an unconjugated, non-therapeutic analog of ponsegromab, supplied strictly for research use only (RUO). With its Fc-silenced design, it is manufactured to in vivo standards, presents low endotoxin, and is produced in scalable milligram (mg) to gram (g) batches for heavy-usage and high-throughput laboratories. It functions as a neutralising and control reagent across in vitro signalling assays and in vivo models of cachexia and metabolic disease, delivering consistent lot-to-lot performance.

Q99988

ICH3002

https://www.imgt.org/mAb-DB/