Peresolimab Biosimilar - Research Grade

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SKU
ICH5221
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$315.00 - $19,890.00

Peresolimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
PD-1
Concentration
5mg/ml
Isotype
Human IgG1 (E356D/M358L)-kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects PD-1
Shipping Conditions
Blue ice
Background
Although PD-1 classically restrains T-cell activity, agonism of this checkpoint is now being explored in autoimmune research. This recombinant anti-human PD-1 monoclonal is an unconjugated, non-therapeutic analog of peresolimab, supplied for research use only (RUO). It is manufactured to in vivo standards with low endotoxin and offered in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Applications include functional assays, checkpoint-engagement and T-cell-modulation studies, reproducible controls, and in vivo models of immune regulation, with the lot-to-lot consistency required for extended, heavy-usage immunology programmes.
Uniprot
Q15116
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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