Dazukibart Biosimilar - Research Grade

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SKU
ICH5220
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$315.00 - $19,890.00

Dazukibart Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
IFNB1
Concentration
5mg/ml
Isotype
Human IgG1 (L234A/L235A/G237A)-kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects IFNB1
Shipping Conditions
Blue ice
Background
Interferon beta (IFNB1) is a type-I interferon that orchestrates antiviral and immunomodulatory responses, of interest across autoimmune and inflammatory research. This recombinant anti-human IFNB1 monoclonal is an unconjugated, non-therapeutic analog of dazukibart, supplied for research use only (RUO). With its Fc-silenced design, it is manufactured to in vivo standards, presents low endotoxin, and is produced in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Use it in functional assays, interferon-neutralisation and signalling studies, reproducible controls, and in vivo models of type-I-interferon-driven disease, with consistency suited to heavy-usage work.
Uniprot
P01574
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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