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Idarucizumab Biosimilar - Research Grade
$315.00 - $19,890.00
Idarucizumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
Pradaxa
Concentration
5mg/ml
Isotype
Human Fab-G1-kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Dabigatran (marketed as Pradaxa) is a direct thrombin inhibitor, and reversal of its anticoagulant activity is an active area of coagulation research. This recombinant anti-dabigatran Fab fragment is an unconjugated, non-therapeutic analog of idarucizumab, supplied for research use only (RUO). Produced to in vivo manufacturing standards and purified to low endotoxin, it is offered in scalable milligram (mg) to gram (g) quantities for high-throughput and heavy-usage laboratories. It is suited to drug-binding and neutralization assays, in vitro functional screening, and in vivo anticoagulant-reversal models, providing a reliable, reproducible reagent.
Other Names
anti-dabigatran,aDabi-Fab,antidote for dabigatran ,dabigatran etexilate mesylate
Specificity
Detects human Pradaxa
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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