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Human IgG4 Fc plus hinge region
$315.00 - $5,200.00
Human IgG4 Fc plus hinge region
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG4 S228P Kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG4 (S228P) Fc-plus-hinge fragment with a kappa-associated framework comprises the hinge-stabilised constant region of human IgG4 without an antigen-binding site, providing a control reagent for Fc-focused studies and Fc-fusion work. The S228P substitution suppresses Fab-arm exchange, and the absence of a variable domain makes the fragment a clean negative reference for separating Fc effects from specific binding in functional and receptor-interaction assays. It is supplied low in endotoxin and suitable for in vivo use, and manufactured in scalable milligram to gram quantities for bulk and high-throughput laboratories. Research use only.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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