Back to Top
Page 2 - Citation Review Articles
-
December 17, 2024
Breakthrough in De Novo Antibody Design Achieves Therapeutic-Grade Properties
A transformative paper from Nabla Bio demonstrates a significant leap forward in computational antibody design, showing that de novo methods can now achieve therapeutic-grade properties without experimental optimization. Their system, called JAM (Joint Atomic Modeling), represents a major...
-
November 05, 2024
Dual Role of cGAS/STING Signaling in Colorectal Cancer Chemotherapy: Friend or Foe?
Introduction
Colorectal cancer (CRC) remains a significant health challenge, with FOLFOX chemotherapy (combining 5-FU, oxaliplatin, and leucovorin) being a first-line treatment. While immunotherapies like...
-
October 14, 2024
Riluzole Enhances Anti-PD-1 Efficacy in Colorectal Cancer by Activating cGAS/STING Signaling
Introduction
Colorectal cancer (CRC) remains a significant health challenge, ranking as the third most common cancer and the second leading cause of cancer-related deaths in the United States...
-
October 14, 2024
Persistent Microglial Activation: A Double-Edged Sword in Latent Cytomegalovirus Infection
Cytomegalovirus (CMV) infection remains a significant health concern, particularly for newborns and immunocompromised individuals. A recent study by Brizić et al. sheds new light on the long-term consequences of CMV infection in the brain, revealing a complex interplay between...
-
September 05, 2024
Uncovering Exhausted T Cell Phenotypes in Autoimmune Diseases: The Crucial Role of HLA Blocking Antibodies
Introduction
The latest study about the role of autoantigen-specific CD4+ T cell phenotypes in several autoimmune diseases opens a new...
-
August 21, 2024
Breakthrough in Cancer Immunotherapy: Multiantigen T-Cell Hybridizers Show Promise in Treating Hematological Malignancies
Introduction
A recent revolutionary study in the journal ACS Nano presents a novel immunotherapy approach to treating haematological...
-
May 30, 2024
Understanding How PGE2 Causes Dendritic Cell Dysfunction in Cancer and Its Possible Treatments
1. Introduction
In the case of malignant tumors or cancer, the immune system fights to survive in the body. However, the most significant molecule is PGE2 (Prostaglandin E2), which often stimulates...
-
March 15, 2024
A Dynamic Duo: How Akkermansia muciniphila and Parabacteroides distasonis Protect Against Inflammatory Bowel Disease
In the ever-evolving field of gut microbiome research, scientists are continuously unraveling the complex relationships between our resident gut bacteria and various health conditions. A recent study by Gaifem et al., published in the journal mBio, sheds...
-
March 01, 2024
Intratumoral Delivery of Interleukin 9 via Oncolytic Vaccinia Virus Elicits Potent Antitumor Effects in Tumor Models
by Junjie Ye, Lingjuan Chen, Julia Waltermire, Jinshun Zhao, Jinghua Ren, Zongsheng Guo, David L. Bartlett, and Zuqiang Liu
Cancers 2024, 16(5), 1021
https://doi.org/10.3390/cancers16051021
Introduction
Researchers at Allegheny...
