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Ralpancizumab Biosimilar - Research Grade
$710.00 - $6,900.00
Ralpancizumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
PCSK9ï؟½
Concentration
5mg/ml
Isotype
IgG2 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q8NBP7
Shipping Conditions
Blue ice
Background
PCSK9 modulates LDL-receptor degradation and is a well-validated target in lipid and cardiovascular research. This human IgG2 kappa antibody is an unconjugated, non-therapeutic analog of ralpancizumab, expressed in CHO cells against human PCSK9. Supplied for research use only, it is purified to low endotoxin for in vivo suitability and manufactured in scalable milligram (mg) to gram (g) quantities for high-throughput laboratories. It is a reliable reagent for PCSK9-blockade assays, LDL-receptor recycling studies, functional readouts, and preclinical models of cholesterol metabolism. Reliable batch-to-batch consistency suits laboratories running extended experimental campaigns.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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