Rituximab Biosimilar – Research Grade [ICH4011]

ichorbio’s Rituximab Biosimilar – Research Grade is manufactured in a cGMP compliant facility.

ichorbio’s research grade rituximab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our rituximab biosimilar – please contact us for pricing.

CD20

n/a

Human IgG1(N297A/E356D/M358L)-Kappa

B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, MS4A1

Humanized

Human

Detects human CD20. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Rituximab. ichorbio’s rituxumab biosimilar is for research use only (RUO).

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Rituximab is a genetically engineered chimeric murine/human monoclonal IgG1 kappa antibody directed against the CD20 antigen. Rituximab has an approximate molecular weight of 145 kD. Rituximab is produced by mammalian cell (Chinese Hamster Ovary).

1.0 – 5.0 mg/ml

Sterile, clear, colorless, preservative-free solution containing polysorbate 80, sodium chloride, sodium citrate. The pH is 6.5. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Rituximab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.