Girentuximab Biosimilar – Research Grade [ICH5013]

ichorbio’s girentuximab biosimilar is for Research Use Only (RUO) and not for therapeutic use.

ichorbio’s RUO girentuximab biosimilar is available in the following sizes:
1mg, 5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar – please contact us for pricing.

Carbonic anhydrase IX

IgG1

CAIX, CA-IX, Carbonic anhydrase 9, CA9

CHO cells

Human

Detects human carbonic anhydrase 9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody girentuximab.

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

RUO girentuximab binds to the extracellular proteoglycan (PG)-like domain, which is unique to CA IX compared to other isoforms and lies adjacent to the catalytic domain. In addition to therapy, girentuximab has also been utilized as an imaging agent.

1.0 – 5.0 mg/ml

Sterile, preservative-free, solution in PBS. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 1.0 EU/mg as determined by the LAL method

This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.