Cetuximab Biosimilar - GAALIE Research Grade

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SKU
ICH4004Fc
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$315.00 - $5,200.00

Cetuximab Biosimilar - GAALIE Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
EGFR
Concentration
5mg/ml
Isotype
Human IgG1 (Mutation)-kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human EGFR.
Shipping Conditions
Blue ice
Background
A key oncogenic driver in many epithelial cancers, the epidermal growth factor receptor (EGFR) is among the most heavily investigated targets in cancer biology. This GAALIE-engineered, research-grade anti-human EGFR recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of cetuximab, with an Fc variant tuned for altered receptor engagement and intended for research use only. Validated for functional assays and produced to in vivo standards as an ultra-pure, low-endotoxin preparation, it is supplied in scalable milligram to gram quantities for high-throughput and bulk laboratories. It supports preclinical work including EGFR-blocking studies, effector-function assays, in vivo tumour models, and biologics and ADC development.
Other Names
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1
Uniprot
P00533
Buffer
ICH3001-100ml ICH3002-100ml ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
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