Bevacizumab Biosimilar – Research Grade [ICH4003]

ichorbio’s Bevacizumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility. ichorbio’s bevacizumab biosimilar is strictly for research use only (RUO).

ichorbio’s research grade bevacizumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg, 100mg
ichorbio regularly manufactures bulk multi-gram amounts of our bevacizumab biosimilar – please contact us for pricing.

VEGF

n/a

IgG1

Vascular Endothelial Growth Factor

Humanized

Human

Detects human VEGF. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Bevacizumab.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Bevacizumab biosimilar is vascular endothelial growth factor directed antibody. Bevacizumab biosimilar is a recombinant humanized monoclonal IgG1 antibody that contains human framework regions and murine complementarity-determining regions. Bevacizumab biosimilar has an approximate molecular weight of 149 kDa. Bevacizumab is produced in a mammalian cell (Chinese Hamster Ovary) expression system in a nutrient medium.

1.0 – 5.0 mg/ml

Sterile, clear or slightly milky white, colorless to light brown liquid, containing trehalose, monobasic sodium phosphate monohydrate, sodium dihydrogen phosphate and Tween 20. pH 6.2. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Bevacizumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.