Drozitumab Biosimilar - Research Grade

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SKU
ICH5491
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Drozitumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
TNFRSF10Bï؟½
Concentration
5mg/ml
Isotype
IgG1 - lambda3
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
O14763
Shipping Conditions
Blue ice
Background
Death receptor 5 (DR5, encoded by TNFRSF10B) is a pro-apoptotic TRAIL receptor whose agonism triggers programmed cell death in tumor cells, a longstanding theme in cancer research. Our research-grade anti-human DR5 recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of drozitumab, provided for research use only (RUO). Crafted to stringent in vivo standards, this ultra-pure, low-endotoxin material is supplied in scalable milligram (mg) to gram (g) quantities to support heavy-usage, high-throughput laboratories. Use it as a control and functional reagent for apoptosis assays, in vitro receptor crosslinking screens, and in vivo tumor models.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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